Concordant vs discordant variation

x2 Concordant pairs and discordant pairs refer to comparing two pairs of data points to see if they "match." The meaning is slightly different depending on if you are finding these pairs from various coefficients (like Kendall's Tau) or if you are performing experimental studies and clinical trials. 1. In Coefficient CalculationsConcordant was defined as discharge disposition agreeing with the CDS tool's recommendation, whereas discordant was defined as discharge disposition disagreeing with the recommendation. We used ...A concordant, or longitudinal type coastline occurs where beds, or layers, of differing rock types are folded into ridges that run parallel to the coast. A discordant coastline occurs where bands of different rock type run perpendicular to the coast. The differing resistance to erosion leads to the formation of headlands and bays. Use this ... Concordant coastlines tend to have fewer bays and headlands. Along the coastline of the Isle of Purbeck in Dorset, there are both discordant and concordant coastlines. The discordant coastline has ...( A) Algorithm used to identify concordant and discordant gene modules. The log fold changes and p-values between groups were calculated with R-package limma. The orthologous genes or genes corresponding to each other (if compared data sets derive from two groups of the same species) were mapped to each other.Mar 07, 2011 · Purpose In diffuse large B-cell lymphoma (DLBCL), prior studies suggest that concordant bone marrow involvement with DLBCL portends a poorer prognosis, whereas discordant bone marrow involvement with small B-cell lymphoma does not. We examined the significance of bone marrow involvement in patients treated in the current era of therapy including rituximab. Patients and Methods We performed a ... Jan 18, 2012 · We used a standardized measure of motor proficiency to objectively examine quantitative variation in motor proficiency in sibling pairs concordant and discordant for ASD. Motor impairment of ... To explore the origins and potential clinical implications of dissimilarities between these two measures of LDL, we examined concordant and discordant subgroups separately, defining discordance as a difference of ≥12 percentile units to make half the population "concordant" (points between the dashed lines in Fig. 1B).This video explains the difference between a concordant and discordant coastline, including the coastal landforms that occur along each and the geological st... Discordant variation observed in 2 twin pairs, referring to a total of 2174 genes enriched in neurodevelopmental processes: Morimoto et al. Blood: 1 (100.0) 11: ... MZ concordant/discordant pairs: Autistic trait/symptoms: Regional cortical volume, surface area and thickness (O)The calculation of the possible concordant ages from discordant age data has been greatly simplified by Wetherill's graphical method of plotting the mole ratios of radiogenic Pb 206 U 238 (N 206 N 238) vs. radiogenic Pb 207 U 235 (N 207 N 235) after correcting for the contaminating common Pb 206 and Pb 207.Mar 01, 2004 · However, only the clinically concordant pairs exhibited concordance in cerebellar gray and white matter volumes. Within the discordant twin pairs, both the twins with autism and their co-twins exhibited frontal, temporal, and occipital white matter volumes that were lower than those of the comparison subjects. Concordant and discordant coastlines. GCSE and A Level Geography Revision.Concordant means to be harmonious and/or agreeable with. So keeping that in mind appendant would be any organization that has a requirement of being a freemason or close relations with a freemason to join. That would be Scottish Rite, Shrine (right now), York Rite, Eastern Star, Grotto, Amaranth, etc.Using a sample of twins extremely discordant and concordant for neuroticism Fullerton et al. (69) identified five loci (at 1q, 4q, 7p, 12q, and 13q) that exceeded the genomewide significance ...TopHat has a --no-discordant command-line option which only report read alignments if both reads in a pair can be mapped, ... and you wanted to filter it to only keep uniqueley mapped, concordant read pairs, you could use two of the options that the samtools view command provides:-q 50 — This filters on the MAPQ field (5th column of SAM file).Considering mortality by concordance, 23/383 (6.0%) of children died in the concordant group and 12/69 (17.4%) of children died in the discordant group (P = 0.001). When considering only the first empiric regimen, 20/338 (5.9%) of children died in the concordant group and 15/113 (13.3%) of children died in the discordant group (P = 0.011).Discordant adjective. (geology) of a differing type of rock cutting across a formation. 'Dikes may be discordant to country rock if they intrude at a high angle to the bedding.'; Discordant adjective. (mathematics) of opposite sign. Discordant adjective. Disagreeing; incongruous; being at variance; clashing; opposing; not harmonious.of variation of less than 5.4 and 5.6 respectively. ... low discordant, concordant and high discordant were obtained within each AFC group. IVF outcomes in each of three groups were analyzed comparing three sub groups using Pearson Chi ... (42% Vs 43.9% and 30% Vs 32.6%). Women with11 0.048 (permutation test, 8 concordant vs. 9 discordant pairs), but not for the cardiac phenotype: p-value = 12 0.568 (6 vs. 11). 13 Mitochondrial function has been primarily studied in mouse models of neurological 22q11DS phenotypes. 14 Our study sets a precedent for considering human mitochondrial variation as a genetic modifier ofArea under curve (AUC) = (Percent Concordant + 0.5 * Percent Tied)/100; Interpretation of Concordant, Discordant and Tied Percent Percent Concordant : Percentage of pairs where the observation with the desired outcome (event) has a higher predicted probability than the observation without the outcome (non-event).usually are concordant (appropriate) relative to the ventri­ cles, no matter whether the AV alignments are concordant or discordant. The tricuspid valve typically connects with the morphologically right ventricle, and the mitral valve connects with the morphologically left ventricle, both with AV concordance and discordance. We distinguish between Variability of DNA methylation between brain and blood was moderately concordant Having identified biological variables that were correlated with nearly 85% of the variability in our DNA methylation data, we next addressed the degree to which methylation varied across individuals, and whether this variability was consistent across tissues.Concordant VS. Discordant Xeno Cardiac Transplantation; The past, present and future trends Hassan Mir Mohammad Sadeghi Assistant Professor of Surgery, Rajaie Cardiovascular, Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran. Received: October 20, 2016; Accepted: October 29, 2016 Available online: 1st November 2016 Jan 15, 2011 · They found discordant relations between IGF1 and growth after rearing temperatures were decreased to 7 °C for fish that had experienced constant 11 °C throughout rearing (1.5 years). However, after 7 weeks of rearing at 7 °C concordant IGF1 and growth (length) relations were re-established across fish at 7 and 11 °C. Area under curve (AUC) = (Percent Concordant + 0.5 * Percent Tied)/100; Interpretation of Concordant, Discordant and Tied Percent Percent Concordant : Percentage of pairs where the observation with the desired outcome (event) has a higher predicted probability than the observation without the outcome (non-event).The predicted mean score of an observation is the sum of the Ordered Values (shown in the "Response Profile" table) minus one, weighted by the corresponding predicted probabilities for that observation; that is, the predicted means score , where is the number of response levels and is the predicted probability of the th (ordered) response.. A pair of observations with different observed ...(4) In late-passage and cloned HUT102 cells, an increase in HTLV production was concordant with a decrease in constitutive interferon production and the loss of mature T lymphocyte antigens. (5) The concordance, sensitivity, and specificity of proxy reports about partners' occupation, smoking, and drinking were examined in relation to self-reports.Microcalcifications alone were significantly more common in discordant than in concordant cancers. A limited number of studies have analyzed prospective independent double reading with respect to discordant and concordant cancers in mammography screening (10 -16). The studies showed discordant interpretation with subsequent cancers in 8.4% ...Dental caries remains the most common chronic disease in children, and the respective etiology is not fully understood. Though Streptococcus mutans is an important factor in the initiation and progression of caries, its presence is not always associated with the disease. The existence of caries discordant populations, in which S. mutans counts do not correlate with caries experience, poses a ...monitoring glucocorticoid taper variation will be essential in future SLE trials. Trail registration numbers NCT02446912 and NCT02446899. INTRODUCTION ... Concordant and discordant subgroups were evaluated for baseline demographics and clinical characteristics, glucocor-ticoid taper, responses from baseline to week 52 across the ...Background This study aimed to identify and resolve discordant variant interpretations across clinical molecular genetic laboratories through the Canadian Open Genetics Repository (COGR), an online collaborative effort for variant sharing and interpretation. Methods Laboratories uploaded variant data to the Franklin Genoox platform. Reports were issued to each laboratory, summarising variants ... jigsaw puzzles for sale uk Variability of DNA methylation between brain and blood was moderately concordant Having identified biological variables that were correlated with nearly 85% of the variability in our DNA methylation data, we next addressed the degree to which methylation varied across individuals, and whether this variability was consistent across tissues.Lastly, only 5% concordant vs. 32.4% discordant twin pairs with type 1 diabetes possessed neither the HLA-DQB1*0302/0201 combination nor the INS Hph I high-risk ... The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM 2 susceptibility locus for type 1 diabetes.In this Video lecture We have tried to Explain-Some Important form of igneous rocks structure.i.e.sills, dikes laccolith, batholith laccolith, xenolith, volc... Discordant variation observed in 2 twin pairs, referring to a total of 2174 genes enriched in neurodevelopmental processes: Morimoto et al. Blood: 1 (100.0) 11: ... MZ concordant/discordant pairs: Autistic trait/symptoms: Regional cortical volume, surface area and thickness (O)Methods: Motor impairment of sibling pairs from 67 ASD-affected families comprising 29 concordant pairings and 48 discordant pairings were assessed using the Bruininks Oseretsky Test of Motor Proficiency, 2nd Edition, a standardized measure of motor proficiency. Pitfalls in the evaluation of aortic valve stenosis. Discordant grading is defined based upon the observation that one parameter suggests a moderate AS while the other suggests a severe AS. Discordant grading is defined either by an AVA <1 cm² while MPG is ≥40 mmHg/PVel <4 m/sec, or by an AVA ≥1 cm² and an MPG ≥40 mmHg/PVel ≥4 m/sec ...The variation pattern lacks the simple harmonious relationships of the pure species. Variation is no longer con­ cordant, it.is DISCORDANT. It was by the discordance or concord­ ance of population variation patterns therefore that we had been able to rec­ ognize introgression in generaand in floras with which we were unfamiliar. In good Genome Scan for Blood Pressure Xu et al. (1999) AJHG 64:1694-1701 367 markers 207 discordant, 258 high concordant, 99 low concordant, defined to be top/bottom age-adjusted population deciles ASPEX, MapMaker/Sibs D2S2387, D11S2019, D15S657, D16S3396, D17S1303 (MLOD>2.0) 19.The role of concordant and discordant comorbidities on performance of self-care behaviors in adults with type 2 diabetes: a systematic review ... . 4 The global age-standardized diabetes prevalence is 9.0% in men and 7.9% in women though there is great regional variation. 5 More than 90% of all DM cases are T2D which is continuously increasing ...11 0.048 (permutation test, 8 concordant vs. 9 discordant pairs), but not for the cardiac phenotype: p-value = 12 0.568 (6 vs. 11). 13 Mitochondrial function has been primarily studied in mouse models of neurological 22q11DS phenotypes. 14 Our study sets a precedent for considering human mitochondrial variation as a genetic modifier ofDental caries remains the most common chronic disease in children, and the respective etiology is not fully understood. Though Streptococcus mutans is an important factor in the initiation and progression of caries, its presence is not always associated with the disease. The existence of caries discordant populations, in which S. mutans counts do not correlate with caries experience, poses a ...Background Bone marrow involvement confers a poor prognosis in patients with diffuse, large, B-cell lymphoma (DLBCL). However, the prognostic significance of concordant and discordant bone marrow involvement in these cases differs. We analysed this further in patients treated with R-CHOP (rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone) at a single institute. Design ... Concordant coastlines tend to have fewer bays and headlands. Along the coastline of the Isle of Purbeck in Dorset, there are both discordant and concordant coastlines. The discordant coastline has ...A Genome Segment Graph, similar to a splice graph [], encodes relationships between genomic segments and a set of reads.A segmentationS of the genome is a partition of the genome into disjoint intervals according to concordant and discordant paired-end alignments with respect to the reference genome. The genome partitioning, edge construction and edge filtering is done in the same way as in Ma ...Background: The American College of Cardiology/American Heart Association and American Society of Echocardiography guidelines recommend assessing several echocardiographic parameters when evaluating mitral regurgitation (MR) severity. These parameters can be discordant, making the assessment of MR challenging. The degree to which echocardiographic parameters of MR severity are concordant is ...(4) In late-passage and cloned HUT102 cells, an increase in HTLV production was concordant with a decrease in constitutive interferon production and the loss of mature T lymphocyte antigens. (5) The concordance, sensitivity, and specificity of proxy reports about partners' occupation, smoking, and drinking were examined in relation to self-reports. role play dress up for toddlers Discordance definition, a discordant state; disagreement; discord. See more.Ah, the whore, mainly containing their mirrors, is this Minerals is in organic, solid, inorganic, solid. Uh, these inorganic solid exists as crystal homogeneous, naturally occurring NATO iron. So these minerals that exist in yours, we usually separated it because these mineral used and the source for the minute the lion. Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder characterized by impaired social communication coupled with stereotyped behaviors and restricted interests. Despite the high concordance rate for diagnosis, there is little information on the magnitude of genetic contributions to specific ASD behaviors.Jan 15, 2011 · They found discordant relations between IGF1 and growth after rearing temperatures were decreased to 7 °C for fish that had experienced constant 11 °C throughout rearing (1.5 years). However, after 7 weeks of rearing at 7 °C concordant IGF1 and growth (length) relations were re-established across fish at 7 and 11 °C. Additional file 8: Figure S5 - Absolute values of concordance in the functional annotation of variation. Numbers of concordant, discordant and unique variants. Concordant indicates variant given same annotation in both sets, discordant indicates the variant is found in both sets but given different annotation, and unique indicates variant is ...Objectives To analyse which mammographic and tumour characteristics led to concordant versus discordant recalls at blinded double reading to further optimise our breast cancer screening programme. Methods We included a consecutive series of 99,013 screening mammograms obtained between July 2013 and January 2015. All mammograms were double read in a blinded fashion. Discordant readings were ...The frequency of minor discrepancies was also significantly higher (p = .04) among studies with a concordant (0.34%) versus discordant (0.29%) subspecialty, with an RR of 1.17 (95% CI, 1.00-1.36; 17.0% increased likelihood of a minor discrepancy for examinations with a concordant versus discordant subspecialty among advanced examinations).Concordant coasts are also known as dalmatian coasts, after the Dalmatian region of Croatia, or Pacific coasts, after the coastline of Chile in South America. Discordant These are where rock strata or structures are aligned at an angle to the coastline. Discordant coasts have a crenellated pattern of projecting headlands and indented bays. Concordant coasts are also known as dalmatian coasts, after the Dalmatian region of Croatia, or Pacific coasts, after the coastline of Chile in South America. Discordant These are where rock strata or structures are aligned at an angle to the coastline. Discordant coasts have a crenellated pattern of projecting headlands and indented bays. Concordance by sex was not related to perceptions of personal (mean 83.4 and 85.1, respectively, for concordant and discordant dyads) or ethnic (mean 52.2 and 52.7, respectively, for concordant and discordant dyads) similarity. Important to note, however, was the wide variability in similarity scores for both concordant and discordant dyads.Information and translations of Discordant coastline in the most comprehensive dictionary definitions resource on the web. ... North of Swanage, the chalk outcrop creates the headland which includes Old Harry Rocks. The converse of a discordant coastline is a concordant coastline. How to pronounce Discordant coastline? Alex. US English. David ...Background This study aimed to identify and resolve discordant variant interpretations across clinical molecular genetic laboratories through the Canadian Open Genetics Repository (COGR), an online collaborative effort for variant sharing and interpretation. Methods Laboratories uploaded variant data to the Franklin Genoox platform. Reports were issued to each laboratory, summarising variants ...Linkage analysis of extremely discordant and concordant sibling pairs identifies quantitativetrait loci that influence variation in the human personality trait neuroticism ... (RGS2) a com-pelling candidate gene for human anxiety phenotypes. Objective: To examine whether variation in RGS2 is as-sociated with intermediate phenotypes for human ...3. A pair of observations is concordant if the subject who is higher on one variable is also higher on the other variable. A pair of observations is discordant if the subject who is higher on one variable is lower on the other variable. Number of concordant pairs: Beginner, Low * Intermediate, Med = 50. Ketelaar ME, Hofstra RMW, Hayden MR. What monozygotic twins discordant for phenotype illustrate about mechanisms influencing genetic forms of neurodegeneration. As monozygotic (MZ) twins are believed to be genetically identical, discordance for disease phenotype between MZ twins has been used in genetic research to understand the contribution of genetic vs environmental factors in disease ...Diagnostic genetic testing was abnormal for 20% of the concordant and 5.6% of the discordant pairs, with no difference in rate of abnormal genetic results between the groups (p = 0.395).Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder characterized by impaired social communication coupled with stereotyped behaviors and restricted interests. Despite the high concordance rate for diagnosis, there is little information on the magnitude of genetic contributions to specific ASD behaviors.19%) had discordant Doppler parame-ters—that is, a valve area of 1.0-1.5 cm2 but a mean gradient <20 mm Hg. Over a median follow-up period of 4.9 years, the discordant AS cohort were less likely to undergo aortic valve replacement (26.7% vs 44.1%) and had higher mortality (60% vs 43%) compared on July 12, 2022 by guest. Protected by copyright.Discordant variation observed in 2 twin pairs, referring to a total of 2174 genes enriched in neurodevelopmental processes: Morimoto et al. Blood: 1 (100.0) 11: ... MZ concordant/discordant pairs: Autistic trait/symptoms: Regional cortical volume, surface area and thickness (O)Another aspect of ventricular interdependence, characteristic of constrictive pericarditis in contrast to restrictive cardiomyopathy, is the discordant variation of right and left ventricular peak systolic pressure levels with respiration.18 In restrictive cardiomyopathy the two pressures vary together, while in constrictive pericarditis they ...Based on the correlation between the topology and the direction of flow, drainage patterns are classified into concordant drainage and discordant or insequent drainage. Concordant drainage patterns A drainage pattern is described as concordant if it correlates to the topology and geology of the area.A Genome Segment Graph, similar to a splice graph [], encodes relationships between genomic segments and a set of reads.A segmentationS of the genome is a partition of the genome into disjoint intervals according to concordant and discordant paired-end alignments with respect to the reference genome. The genome partitioning, edge construction and edge filtering is done in the same way as in Ma ...CNV-Seq results were concordant for 14 (87.5%) of the 16 gross chromosomal abnormalities identified by karyotyping, including 11 autosomal trisomies and three sex chromosomal aneuploidies (45,X). Of the two discordant results, a 69,XXX polyploidy was missed by CNV-Seq, although supporting STR marker analysis confirmed the triploidy.were assigned randomly to nouns within a 3 (concordant, discordant, neutral) 3 2 (masculine vs feminine noun) 3 2 (transparent vs opaque noun) design, which permits a comparison of facilitation (RTs for concordant vs neutral pairs) and inhibition (RTs for discordant vs neutral pairs). Target nouns were never repeated within participants.The variation pattern lacks the simple harmonious relationships of the pure species. Variation is no longer con­ cordant, it.is DISCORDANT. It was by the discordance or concord­ ance of population variation patterns therefore that we had been able to rec­ ognize introgression in generaand in floras with which we were unfamiliar. In good The specific discordant topologies most affected by SPILS (topologies 6-9) showed false positive rates more than 5% (Fig. 4b). The concordant topology also showed a very slightly lower value of estimated d N / d S than the average d N / d S of the discordant topologies (⁠ 0.491 ± 0.005 vs. 0.496 ± 0.001 ⁠).Methods: Motor impairment of sibling pairs from 67 ASD-affected families comprising 29 concordant pairings and 48 discordant pairings were assessed using the Bruininks Oseretsky Test of Motor Proficiency, 2nd Edition, a standardized measure of motor proficiency. Uranium-bearing minerals that give lead-uranium and lead - lead ages that are essentially in agreement, i.e. concordant, generally are considered to have had a relatively simple geologic history and to have been unaltered since their deposition. The concordant ages obtained on such materials are, therefore, assumed to approach closely the actual age of the minerals. Many uranium-bearing ...3. A pair of observations is concordant if the subject who is higher on one variable is also higher on the other variable. A pair of observations is discordant if the subject who is higher on one variable is lower on the other variable. Number of concordant pairs: Beginner, Low * Intermediate, Med = 50. Discordant adjective. (geology) of a differing type of rock cutting across a formation. 'Dikes may be discordant to country rock if they intrude at a high angle to the bedding.'; Discordant adjective. (mathematics) of opposite sign. Discordant adjective. Disagreeing; incongruous; being at variance; clashing; opposing; not harmonious.Discordance, in genetics typically means that a similar trait is not shared between twin members. Studies of twins have shown that genetic traits of monozygotic twins are fully concordant whereas in dizygotic twins, half of genetic traits are concordant, while the other half are discordant.The specific discordant topologies most affected by SPILS (topologies 6-9) showed false positive rates more than 5% (Fig. 4b). The concordant topology also showed a very slightly lower value of estimated d N / d S than the average d N / d S of the discordant topologies (⁠ 0.491 ± 0.005 vs. 0.496 ± 0.001 ⁠).(4) In late-passage and cloned HUT102 cells, an increase in HTLV production was concordant with a decrease in constitutive interferon production and the loss of mature T lymphocyte antigens. (5) The concordance, sensitivity, and specificity of proxy reports about partners' occupation, smoking, and drinking were examined in relation to self-reports.The variation pattern lacks the simple harmonious relationships of the pure species. Variation is no longer con­ cordant, it.is DISCORDANT. It was by the discordance or concord­ ance of population variation patterns therefore that we had been able to rec­ ognize introgression in generaand in floras with which we were unfamiliar. In good The hospital of admission was one of the strongest determinants of guideline concordance and accounted for one-fifth of the total variation in the blood glucose level at which insulin infusions were initiated. We did not identify associations between the hospital rate of guideline-concordant insulin use and hospital mortality.All samples were drawn simultaneously. A polynomial fit correlating aPTT and anti-Xa with a 99% confidence limit was designed. Paired aPTT/anti-Xa values were grouped according to whether the paired values fell within or outside of the concordant area. Patients were placed into groups based on concordance status, and clinical outcomes were ...Information and translations of Discordant coastline in the most comprehensive dictionary definitions resource on the web. ... North of Swanage, the chalk outcrop creates the headland which includes Old Harry Rocks. The converse of a discordant coastline is a concordant coastline. How to pronounce Discordant coastline? Alex. US English. David ...Jan 19, 2016 · A drainage pattern is described as concordant if it correlates to the topology and geology of the area. In simple words: In a concordant drainage pattern, the path of the river is highly dependent on the slope of the river and topography. Concordant drainage patterns are the most commonly found drainage patterns and are classified into many types. nsi due trap 24 Using a sample of twins extremely discordant and concordant for neuroticism Fullerton et al. (69) identified five loci (at 1q, 4q, 7p, 12q, and 13q) that exceeded the genomewide significance ...Although it may represent a normal physiological variation, high degrees of discrepancy in fetal growth have been associated with poor perinatal outcome. 3-13 In view of this association, ... Only studies reporting the risk of morbidity in discordant vs concordant twins, and from which the raw numbers to calculate the risk of every explored ...For concordant modules, the control modules contained only non-concordant genes (including discordant genes, non-regulated genes or genes with significant differences only in one organism); for ...If the distance between R1 and R2 is outside 500bp (+/- 1SD) or they relative orientation is not Forward/Reverse thy will be called as discordant pairs. If R1 (or R2) alone are aligned, this will...Jan 01, 2016 · Left bundle branch block can be further classified into discordant and concordant. These subtypes carry clinical significance. • Discordant pattern in patients with LBBB is associated with lower LVEF, wider QRS, larger LA size, moderate to severe mitral and tricuspid regurgitation, CKD, CAD, and had more frequently underwent CABG. 3. A pair of observations is concordant if the subject who is higher on one variable is also higher on the other variable. A pair of observations is discordant if the subject who is higher on one variable is lower on the other variable. Number of concordant pairs: Beginner, Low * Intermediate, Med = 50. Concordant: Ordered in the same way. Discordant: Ordered differently. Spearman rank correlation: Spearman rank correlation is a non-parametric test that is used to measure the degree of association between two variables. The Spearman rank correlation test does not carry any assumptions about the distribution of the data and is the appropriate ...Define nonconcordant. Nonconcordant as a adjective means Discordant ; inharmonious ; disconsonant ; not in keeping with; not agreeable with; disagree....In this study, we sought to identify samples that gave clearly discordant MRD results using different tests. Normal variation is considered a <0.5 log difference. Consequently, when the variation between results was ≤1 log, the results were scored as concordant; discordant samples were defined as those for which the MRD levels differed by >1 log.The prevalence of discordant compared with concordant phenotypes was significantly different (P < 10 −15 ... database and to a database of 462 sequenced human gut microbes (table S3). To visualize the variation in this data set, we used principal coordinates analysis of Hellinger distances computed from the KEGG enzyme commission ...(4) In late-passage and cloned HUT102 cells, an increase in HTLV production was concordant with a decrease in constitutive interferon production and the loss of mature T lymphocyte antigens. (5) The concordance, sensitivity, and specificity of proxy reports about partners' occupation, smoking, and drinking were examined in relation to self-reports. discordant definition: 1. producing an unpleasant sound 2. used to describe something that is not in agreement with…. Learn more.\(\tau\) = -1 if all pairs are discordant; \(\tau\) = 0 if the numbers of concordant and discordant pairs are equal and \(\tau\) = 1 if all pairs are concordant. Kendall's Tau-B & Tau-C. Our first method for computing Kendall's Tau only works if each company falls into a different revenue category. This holds for the 2014 and 2015 data.discordant definition: 1. producing an unpleasant sound 2. used to describe something that is not in agreement with…. Learn more.Both concordant and discordant patterns were seen in 2/15 cases by BMB (13%) and 1/16 by FCM (6%). Figure 1 presents event-free survival (EFS) and overall survival (OS) analysis regarding each technique (median follow-up 29 months, 0.3-97). Neither focal nor diffuse PET patterns were related with outcome (1A).The role of concordant and discordant comorbidities on performance of self-care behaviors in adults with type 2 diabetes: a systematic review ... . 4 The global age-standardized diabetes prevalence is 9.0% in men and 7.9% in women though there is great regional variation. 5 More than 90% of all DM cases are T2D which is continuously increasing ...Concordant coastlines tend to have fewer bays and headlands. Along the coastline of the Isle of Purbeck in Dorset, there are both discordant and concordant coastlines. The discordant coastline has ...PURPOSE The purpose of this study was to examine the association between the prevalence of both diabetes-concordant and diabetes-discordant conditions and the quality of diabetes care at the family practice level in England. We hypothesized that the prevalence of concordant (or discordant) conditions would be associated with better (or worse) quality of diabetes care. METHODS We conducted a ... The concordant-discordant model does not explain the patterns of association between the prevalence of chronic conditions and the quality of diabetes care provided by family practices in England. Even so, the strength of the associations and their consistency across different types of practices, quality of care domains, and measures support the ...Variability of DNA methylation between brain and blood was moderately concordant Having identified biological variables that were correlated with nearly 85% of the variability in our DNA methylation data, we next addressed the degree to which methylation varied across individuals, and whether this variability was consistent across tissues.The hospital of admission was one of the strongest determinants of guideline concordance and accounted for one-fifth of the total variation in the blood glucose level at which insulin infusions were initiated. We did not identify associations between the hospital rate of guideline-concordant insulin use and hospital mortality.Jun 17, 2021 · A concordant infiltration was seen in 10/15 cases by BMB (67%) and 4/16 by FCM (25%), whereas 3/15 (20%) and 11/16 (69%) presented a discordant indolent involvement by BMB and FCM, respectively. Both concordant and discordant patterns were seen in 2/15 cases by BMB (13%) and 1/16 by FCM (6%). Aim: Although motor impairment is frequently observed in children with autism spectrum disorders (ASD), the manner in which these impairments aggregate in families affected by autism is unknown. We used a standardized measure of motor proficiency to objectively examine quantitative variation in motor proficiency in sibling pairs concordant and discordant for ASD.Considering mortality by concordance, 23/383 (6.0%) of children died in the concordant group and 12/69 (17.4%) of children died in the discordant group (P = 0.001). When considering only the first empiric regimen, 20/338 (5.9%) of children died in the concordant group and 15/113 (13.3%) of children died in the discordant group (P = 0.011).Ah, the whore, mainly containing their mirrors, is this Minerals is in organic, solid, inorganic, solid. Uh, these inorganic solid exists as crystal homogeneous, naturally occurring NATO iron. So these minerals that exist in yours, we usually separated it because these mineral used and the source for the minute the lion. Discordant adjective. (geology) of a differing type of rock cutting across a formation. 'Dikes may be discordant to country rock if they intrude at a high angle to the bedding.'; Discordant adjective. (mathematics) of opposite sign. Discordant adjective. Disagreeing; incongruous; being at variance; clashing; opposing; not harmonious.Jan 15, 2011 · They found discordant relations between IGF1 and growth after rearing temperatures were decreased to 7 °C for fish that had experienced constant 11 °C throughout rearing (1.5 years). However, after 7 weeks of rearing at 7 °C concordant IGF1 and growth (length) relations were re-established across fish at 7 and 11 °C. Ketelaar ME, Hofstra RMW, Hayden MR. What monozygotic twins discordant for phenotype illustrate about mechanisms influencing genetic forms of neurodegeneration. As monozygotic (MZ) twins are believed to be genetically identical, discordance for disease phenotype between MZ twins has been used in genetic research to understand the contribution of genetic vs environmental factors in disease ...Microcalcifications alone were significantly more common in discordant than in concordant cancers. A limited number of studies have analyzed prospective independent double reading with respect to discordant and concordant cancers in mammography screening (10 -16). The studies showed discordant interpretation with subsequent cancers in 8.4% ...Diagnostic genetic testing was abnormal for 20% of the concordant and 5.6% of the discordant pairs, with no difference in rate of abnormal genetic results between the groups (p = 0.395).A concordant result was defined when the imaging and pathology results concluded same diagnosis and a discordant result when they did not match. All histopathology results were reviewed and a decision was made regarding concordant/discordant biopsy results and recommendations given for further management of all patients. A concordant coastline is where the same rock runs along the length of the coast. Concordant coastlines tend to have fewer bays and headlands. Find out more about concordant coastlines. ... What is a discordant coastline? Explain the formation of bays and headlands. Scroll to top.Discordance definition, a discordant state; disagreement; discord. See more.19%) had discordant Doppler parame-ters—that is, a valve area of 1.0-1.5 cm2 but a mean gradient <20 mm Hg. Over a median follow-up period of 4.9 years, the discordant AS cohort were less likely to undergo aortic valve replacement (26.7% vs 44.1%) and had higher mortality (60% vs 43%) compared on July 12, 2022 by guest. Protected by copyright.PMID: 25977707 Concordant and discordant DNA methylation signatures of aging in human blood and brain Pau Farré,Meaghan J Jones,Michael J Meaney,Eldon Emberly,Gustavo Turecki,and Michael S Kobor Pau Farré Department of Physics, Simon Fraser University, 8888 University Drive, Burnaby, BC V5A 1S6 Canada Find articles by Pau Farré Meaghan J JonesAutism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder characterized by impaired social communication coupled with stereotyped behaviors and restricted interests. Despite the high concordance rate for diagnosis, there is little information on the magnitude of genetic contributions to specific ASD behaviors.Mar 07, 2011 · Purpose In diffuse large B-cell lymphoma (DLBCL), prior studies suggest that concordant bone marrow involvement with DLBCL portends a poorer prognosis, whereas discordant bone marrow involvement with small B-cell lymphoma does not. We examined the significance of bone marrow involvement in patients treated in the current era of therapy including rituximab. Patients and Methods We performed a ... (4) In late-passage and cloned HUT102 cells, an increase in HTLV production was concordant with a decrease in constitutive interferon production and the loss of mature T lymphocyte antigens. (5) The concordance, sensitivity, and specificity of proxy reports about partners' occupation, smoking, and drinking were examined in relation to self-reports.The concordant partial area under the ROC curve was proposed and unlike previous partial measure alternatives, it maintains the characteristics of the AUC. ... Our partial measures are tested for validity on a classic ROC example from Fawcett, a variation thereof, and two real-life benchmark data sets in breast cancer: the Wisconsin and ...Concordant pairs and discordant pairs refer to comparing two pairs of data points to see if they "match." The meaning is slightly different depending on if you are finding these pairs from various coefficients (like Kendall's Tau) or if you are performing experimental studies and clinical trials. 1. In Coefficient CalculationsOur study also suggests that Hispanic-discordant pairs were more likely to receive breast and colorectal cancer screening as compared to concordant pairs. The study by Jerant and colleagues that examined the association between patient-provider gender, race or ethnicity, and dual concordance with healthcare measures also reported no evidence ...The meaning of CONCORDANT is consonant, agreeing. How to use concordant in a sentence. consonant, agreeing… See the full definition. SINCE 1828. GAMES & QUIZZES THESAURUS WORD OF THE ... similar with respect to one or more particular characters — compare discordant. Other Words from concordant. concordance \- ᵊn(t)s \ noun. More from ...Results Among 194 157 patients with type 2 diabetes included in the study, 45.2% had only concordant comorbidities, 30.6% concordant and discordant, 2.7% only discordant, and 13.0% had ≥1 advanced comorbidity. Mean HbA 1c was 7.7% among 18-44 year-olds versus 6.9% among ≥75 year-olds, and was higher among patients with comorbidities: 7.3% with concordant only, 7.1% with discordant only ...• There is significant variation in validation practices for IHC assays. ... (range 74-92%), with 2 of 5 studies >90% concordant. (Boers, 2011; Mayr, 2009; Moelans, 2010; O'Grady, 2010; van der Vegt, 2009) ... stratified by number of observed discordant samples . 2x2 contingency table of a 40 tissue validation set thatWe live in a world of incredible linguistic diversity; nearly 7000 languages are spoken globally and at least 350 are spoken in the United States. Language-concordant care enhances trust between patients and physicians, optimizes health outcomes, and advances health equity for diverse populations. However, historical and contemporary trauma have impaired trust between communities of color ...We live in a world of incredible linguistic diversity; nearly 7000 languages are spoken globally and at least 350 are spoken in the United States. Language-concordant care enhances trust between patients and physicians, optimizes health outcomes, and advances health equity for diverse populations. However, historical and contemporary trauma have impaired trust between communities of color ...19%) had discordant Doppler parame-ters—that is, a valve area of 1.0-1.5 cm2 but a mean gradient <20 mm Hg. Over a median follow-up period of 4.9 years, the discordant AS cohort were less likely to undergo aortic valve replacement (26.7% vs 44.1%) and had higher mortality (60% vs 43%) compared on July 12, 2022 by guest. Protected by copyright.The researchers found that the first component (PC1) reflected a concordant phenotypic model of the skeleton, while PC2 and PC3 were discordant for distal radius versus spine and hip and for spine ...Psychology self-research report requirement. 1. APA Format. 2. 5-6 pages. 3. No plagiarism. 4. With reference. 5. Four variables you will look at: study, sleep, two measures of emotion/moodThis project was a retrospective analysis of veterans with diabetes identified from FY1998-2010, Veterans were classified into 5 chronic comorbid illness groups (CCIG) using a competing demands framework by Piette and Kerr: none, only concordant (DM related), only discordant (non-DM related), both, or dominant (short life expectancy).Microcalcifications alone were significantly more common in discordant than in concordant cancers. A limited number of studies have analyzed prospective independent double reading with respect to discordant and concordant cancers in mammography screening (10 -16). The studies showed discordant interpretation with subsequent cancers in 8.4% ...These dates are 38 and 39 % discordant, as measured by the ratio of the 206 Pb/ 238 U and 207 Pb/ 235 U dates (analytical results are provided in table S1). The rim yields concordant 206 Pb/ 238 U dates of 149 ± 2 and 152 ± 2 Ma (2σ uncertainty; Fig. 2). U and Th concentrations measured from the core and rim domains differ considerably.( A) Algorithm used to identify concordant and discordant gene modules. The log fold changes and p-values between groups were calculated with R-package limma. The orthologous genes or genes corresponding to each other (if compared data sets derive from two groups of the same species) were mapped to each other. aston martin cygnet pourquoi Microcalcifications alone were significantly more common in discordant than in concordant cancers. A limited number of studies have analyzed prospective independent double reading with respect to discordant and concordant cancers in mammography screening (10 -16). The studies showed discordant interpretation with subsequent cancers in 8.4% ...Concordant coasts are also known as dalmatian coasts, after the Dalmatian region of Croatia, or Pacific coasts, after the coastline of Chile in South America. Discordant These are where rock strata or structures are aligned at an angle to the coastline. Discordant coasts have a crenellated pattern of projecting headlands and indented bays.Concordant pairs and discordant pairs refer to comparing two pairs of data points to see if they "match."The meaning is slightly different depending on if you are finding these pairs from various coefficients (like Kendall's Tau). Kendall's Tau is a non-parametric measure of relationships between columns of ranked data.Belonging to the Concordant and discordant subgroup was related to meeting the LDL treatment target (OR 1.31, CI 1.00-1.72). Multimorbidity, including cardiovascular risk and the musculoskeletal disease burden, was extremely prevalent among the T2D patients who consulted primary health care. Primary care clinicians should survey the possible ...Basal-like and classical subtype calls were concordant in 88% of patient samples, and survival outcomes were significantly different (P < 0.05) between prognostic subtypes.Twelve percent of tumors had subtype-discordant calls across the different methods, showing intermediate survival in univariate and multivariate survival analyses.In the Concordant A and Concordant I groups, the intrapair mean within each group was calculated and the difference between the groups was verified by the analysis of variance test (p < .001). In the discordant PA group, the Wilcoxon test (p < .05) was applied for intrapair analysis, that is, comparing the active twin versus the inactive twin.Pitfalls in the evaluation of aortic valve stenosis. Discordant grading is defined based upon the observation that one parameter suggests a moderate AS while the other suggests a severe AS. Discordant grading is defined either by an AVA <1 cm² while MPG is ≥40 mmHg/PVel <4 m/sec, or by an AVA ≥1 cm² and an MPG ≥40 mmHg/PVel ≥4 m/sec ...Introduction Focused parathyroidectomy is the treatment of choice for patients with concordant positive imaging. Bilateral cervical exploration is performed for cases with discordant imaging, yet more than 70% of those cases are the result of a single-gland disease. As focused parathyroidectomy is generally costless and harmless, for cases with discordant imaging, we tried to determine whether ...Using a Delphi study method, Magnan and colleagues 38 identified 12 concordant and 50 discordant comorbidities in DM. The findings from this study suggested that concordant chronic conditions are more easily managed because care goals are similar and more likely to be identified and addressed by care providers. To explore the origins and potential clinical implications of dissimilarities between these two measures of LDL, we examined concordant and discordant subgroups separately, defining discordance as a difference of ≥12 percentile units to make half the population "concordant" (points between the dashed lines in Fig. 1B).Dive into the research topics of 'Phenotypically Concordant and Discordant Monozygotic Twins Display Different DNA Copy-Number-Variation Profiles.'. Together they form a unique fingerprint. DNA Copy Number Variations Medicine & Life Sciences 100% Dec 19, 2019 · A basic summary of discordant phylogeographic patterns. In this case, the different species do not show identical patterns in evolutionary history (B), either within timing (e.g. fish vs. deer) or in how populations were isolated (e.g. fish vs. birds). This might suggest that there is a more complex interaction between the environment and ... Discordance definition, a discordant state; disagreement; discord. See more.Basal-like and classical subtype calls were concordant in 88% of patient samples, and survival outcomes were significantly different (P < 0.05) between prognostic subtypes.Twelve percent of tumors had subtype-discordant calls across the different methods, showing intermediate survival in univariate and multivariate survival analyses.Concordant Discordant Type A X=1 Discordant Type B Concordant X=2 Y=1 Y=2 Grand Total Paired Contingency Table This test employs a 2X2 contingency table in which pairs of observations such as in treatments of "before" versus "after" observations are exactly paired for individuals within a study. Analogy with the paired t-testGaps in guideline concordant use of diagnostic tests among lung cancer patients. ... We surveyed pulmonologists and thoracic surgeons to understand the reasons underlying discordant and variable invasive nodal staging in lung cancer within the United States. Specifically, we sought (1) to determine physician knowledge, attitudes, and beliefs ...discordant: [adjective] being at variance : disagreeing. quarrelsome. Feb 17, 2022 · Dental caries remains the most common chronic disease in children, and the respective etiology is not fully understood. Though Streptococcus mutans is an important factor in the initiation and progression of caries, its presence is not always associated with the disease. The existence of caries discordant populations, in which S. mutans counts do not correlate with caries experience, poses a ... discordant: [adjective] being at variance : disagreeing. quarrelsome. Objectives To investigate the occurrence of discordant grading in patients with moderate AS (defined by an AVA between 1.0 cm² and 1.5 cm² but with an MG <20 mm Hg) and how these patients compare with those with concordant grading moderate AS (AVA between 1.0 cm² and 1.5 cm² and MG ≥20 mm Hg) in terms of clinical outcomes. Results Among 194 157 patients with type 2 diabetes included in the study, 45.2% had only concordant comorbidities, 30.6% concordant and discordant, 2.7% only discordant, and 13.0% had ≥1 advanced comorbidity. Mean HbA 1c was 7.7% among 18-44 year-olds versus 6.9% among ≥75 year-olds, and was higher among patients with comorbidities: 7.3% with concordant only, 7.1% with discordant only ...The Concordant Publishing Concern is a non-denominational, non-profit association founded for the purpose of disseminating the facts and truths of the ancient manuscripts of the Scriptures. Our research efforts are centered upon the many issues involved in discovering the meaning of the original Scripture terms themselves.Lastly, only 5% concordant vs. 32.4% discordant twin pairs with type 1 diabetes possessed neither the HLA-DQB1*0302/0201 combination nor the INS Hph I high-risk ... The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM 2 susceptibility locus for type 1 diabetes.The mean age of women with discordant growth twins was 31.4[+ or -]5.6 years, whereas in concordant pregnancy group it was 30.93[+ or -]4.8 years. A RETROSPECTIVE STUDY OF DISCORDANT TWIN GROWTH IN DICHORIONIC TWIN PREGNANCIES AND RISK OF PRETERM DELIVERY AT SPLIT UNIVERSITY HOSPITAL CENTRE: THREE-YEAR EXPERIENCE kieran tierney transfermarkt However, only the clinically concordant pairs exhibited concordance in cerebellar gray and white matter volumes. Within the discordant twin pairs, both the twins with autism and their co-twins exhibited frontal, temporal, and occipital white matter volumes that were lower than those of the comparison subjects.Spearman's rank correlation plot of cell frequencies for CMV concordant negative (n = 8, medians of random repeats reported; see methods) vs. CMV discordant (n = 5) twins. Each dot represents one cell type. The thick black line represents values at which both CMV −/+ and −/− twins have the exact same Spearman's rank correlation.The variation pattern lacks the simple harmonious relationships of the pure species. Variation' is no longer con-cordant, it is DISCORDANT. It was by the discordance or concord-ance of population -variation patterns therefore that we had been able to rec-ognize introgression in genera and in floras with which we were unfamiliar. In goodBowtie 2 is often the first step in pipelines for comparative genomics, including for variation calling, ChIP-seq, RNA-seq, BS-seq. Bowtie 2 and Bowtie ... By default, Bowtie 2 searches for both concordant and discordant alignments, though searching for discordant alignments can be disabled with the --no-discordant option. Mixed mode: paired ...Batholith: a large irregular discordant intrusion. Chonolith: an irregularly-shaped intrusion with a demonstrable base. Cupola: a dome-shaped projection from the top of a large subterranean intrusion. Dike: a relatively narrow tabular discordant body, often nearly vertical.A concordant, or longitudinal type coastline occurs where beds, or layers, of differing rock types are folded into ridges that run parallel to the coast. A discordant coastline occurs where bands of different rock type run perpendicular to the coast. The differing resistance to erosion leads to the formation of headlands and bays. Use this ... Mar 07, 2011 · Purpose In diffuse large B-cell lymphoma (DLBCL), prior studies suggest that concordant bone marrow involvement with DLBCL portends a poorer prognosis, whereas discordant bone marrow involvement with small B-cell lymphoma does not. We examined the significance of bone marrow involvement in patients treated in the current era of therapy including rituximab. Patients and Methods We performed a ... Another aspect of ventricular interdependence, characteristic of constrictive pericarditis in contrast to restrictive cardiomyopathy, is the discordant variation of right and left ventricular peak systolic pressure levels with respiration.18 In restrictive cardiomyopathy the two pressures vary together, while in constrictive pericarditis they ...discordant: [adjective] being at variance : disagreeing. quarrelsome. Jun 17, 2021 · A concordant infiltration was seen in 10/15 cases by BMB (67%) and 4/16 by FCM (25%), whereas 3/15 (20%) and 11/16 (69%) presented a discordant indolent involvement by BMB and FCM, respectively. Both concordant and discordant patterns were seen in 2/15 cases by BMB (13%) and 1/16 by FCM (6%). Monozygotic (MZ) twins share nearly all of their genetic variants and many similar environments before and after birth. However, they can also show phenotypic discordance for a wide range of traits. Differences at the epigenetic level may account for such discordances. It is well established that epigenetic states can contribute to phenotypic variation, including disease. Epigenetic states are ...Feb 17, 2022 · Dental caries remains the most common chronic disease in children, and the respective etiology is not fully understood. Though Streptococcus mutans is an important factor in the initiation and progression of caries, its presence is not always associated with the disease. The existence of caries discordant populations, in which S. mutans counts do not correlate with caries experience, poses a ... The variation pattern lacks the simple harmonious relationships of the pure species. Variation is no longer con­ cordant, it.is DISCORDANT. It was by the discordance or concord­ ance of population variation patterns therefore that we had been able to rec­ ognize introgression in generaand in floras with which we were unfamiliar. In good Jun 25, 2018 · This actually indicates that there is discordant overlap (as confirmed in Fig. 5c), yet the interpretation of the colors is counterintuitive. The Stratified method (Fig. 5c), however, captures the true behavior of the studies. We can see that the discordant quadrants do have significant overlap, while the concordant quadrants do not. Lastly, only 5% concordant vs. 32.4% discordant twin pairs with type 1 diabetes possessed neither the HLA-DQB1*0302/0201 combination nor the INS Hph I high-risk ... The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM 2 susceptibility locus for type 1 diabetes.Lastly, only 5% concordant vs. 32.4% discordant twin pairs with type 1 diabetes possessed neither the HLA-DQB1*0302/0201 combination nor the INS Hph I high-risk ... The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM 2 susceptibility locus for type 1 diabetes.\(\tau\) = -1 if all pairs are discordant; \(\tau\) = 0 if the numbers of concordant and discordant pairs are equal and \(\tau\) = 1 if all pairs are concordant. Kendall's Tau-B & Tau-C. Our first method for computing Kendall's Tau only works if each company falls into a different revenue category. This holds for the 2014 and 2015 data.Genome Scan for Blood Pressure Xu et al. (1999) AJHG 64:1694-1701 367 markers 207 discordant, 258 high concordant, 99 low concordant, defined to be top/bottom age-adjusted population deciles ASPEX, MapMaker/Sibs D2S2387, D11S2019, D15S657, D16S3396, D17S1303 (MLOD>2.0) 19.If the distance between R1 and R2 is outside 500bp (+/- 1SD) or they relative orientation is not Forward/Reverse thy will be called as discordant pairs. If R1 (or R2) alone are aligned, this will...Jan 15, 2011 · They found discordant relations between IGF1 and growth after rearing temperatures were decreased to 7 °C for fish that had experienced constant 11 °C throughout rearing (1.5 years). However, after 7 weeks of rearing at 7 °C concordant IGF1 and growth (length) relations were re-established across fish at 7 and 11 °C. The frequency of concordant and discordant student responses was described by combining identity items with items that explored responses about practice role, setting and future direction. ... (CCEs) (responsible for the accreditation of chiropractic institutions worldwide) may also explain some of the regional variation in student dissonance ...The prevalence of discordant compared with concordant phenotypes was significantly different (P < 10 −15 ... database and to a database of 462 sequenced human gut microbes (table S3). To visualize the variation in this data set, we used principal coordinates analysis of Hellinger distances computed from the KEGG enzyme commission ...However, when the measurements of FFR and NHPR are discordant (NHPRs+/FFR− or NHPRs−/FFR+) (as in ≈20% of cases), 9 the operator is ... deferred negative concordant and deferred discordant groups. Despite a prior study from the same registry 12 indicating nearly numerical equivalence among all of the diastolic NHPRs, the present study ...Jun 03, 2020 · While concordant phenotypes of non-VI/non-OB and VI/OB had a clear separation of disease burden in terms of PROs and emphysema, the discordant phenotypes of VI/non-OB and non-VI/OB resembled more their VI status than their OB status. Our data suggests that up to 19% of COPD subjects may be misclassified using SP. Jan 15, 2011 · They found discordant relations between IGF1 and growth after rearing temperatures were decreased to 7 °C for fish that had experienced constant 11 °C throughout rearing (1.5 years). However, after 7 weeks of rearing at 7 °C concordant IGF1 and growth (length) relations were re-established across fish at 7 and 11 °C. A concordant, or longitudinal type coastline occurs where beds, or layers, of differing rock types are folded into ridges that run parallel to the coast. A discordant coastline occurs where bands of different rock type run perpendicular to the coast. The differing resistance to erosion leads to the formation of headlands and bays. Use this ... Careful attention to baseline disease activity and monitoring glucocorticoid taper variation will be essential in future SLE trials. Trial registration numbers [NCT02446912][1] and [NCT02446899][2]. ... Concordant and discordant subgroups were evaluated for baseline demographics and clinical characteristics, glucocorticoid taper, responses from ...Spearman's rank correlation plot of cell frequencies for CMV concordant negative (n = 8, medians of random repeats reported; see methods) vs. CMV discordant (n = 5) twins. Each dot represents one cell type. The thick black line represents values at which both CMV −/+ and −/− twins have the exact same Spearman's rank correlation.Although it may represent a normal physiological variation, high degrees of discrepancy in fetal growth have been associated with poor perinatal outcome. 3-13 In view of this association, ... Only studies reporting the risk of morbidity in discordant vs concordant twins, and from which the raw numbers to calculate the risk of every explored ...Methods: Motor impairment of sibling pairs from 67 ASD-affected families comprising 29 concordant pairings and 48 discordant pairings were assessed using the Bruininks Oseretsky Test of Motor Proficiency, 2nd Edition, a standardized measure of motor proficiency. The concordant-discordant model does not explain the patterns of association between the prevalence of chronic conditions and the quality of diabetes care provided by family practices in England. Even so, the strength of the associations and their consistency across different types of practices, quality of care domains, and measures support the ...Belonging to the Concordant and discordant subgroup was related to meeting the LDL treatment target (OR 1.31, CI 1.00-1.72). Multimorbidity, including cardiovascular risk and the musculoskeletal disease burden, was extremely prevalent among the T2D patients who consulted primary health care. Primary care clinicians should survey the possible ...Feb 14, 2011 · To explore the origins and potential clinical implications of dissimilarities between these two measures of LDL, we examined concordant and discordant subgroups separately, defining discordance as a difference of ≥12 percentile units to make half the population “concordant” (points between the dashed lines in Fig. 1B). were assigned randomly to nouns within a 3 (concordant, discordant, neutral) 3 2 (masculine vs feminine noun) 3 2 (transparent vs opaque noun) design, which permits a comparison of facilitation (RTs for concordant vs neutral pairs) and inhibition (RTs for discordant vs neutral pairs). Target nouns were never repeated within participants.concordant pairs, however, the ascertainment probability is more complicated. There are three ways to ascertain concordant pairs. First, twin 1 may be ascertained but twin 2 is not ascertained. This will occur with frequency π(1 - π). Second, twin two may be ascertained while twin 1 remains unascertained. This also occurs with frequency π(1 ...Twin studies are studies conducted on identical or fraternal twins. They aim to reveal the importance of environmental and genetic influences for traits, phenotypes, and disorders.Twin research is considered a key tool in behavioral genetics and in content fields, from biology to psychology. Twin studies are part of the broader methodology used in behavior genetics, which uses all data that ...Lastly, only 5% concordant vs. 32.4% discordant twin pairs with type 1 diabetes possessed neither the HLA-DQB1*0302/0201 combination nor the INS Hph I high-risk ... The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM 2 susceptibility locus for type 1 diabetes.Parent-Child Discordant. Parent-Child Concordant. Trio, child must be affected. Family pair other than Sibs or Parent-Child. Family with at least 3 members, including 1 proband, not a trio. Control family with at least 3 members, no proband. Identical Twins, Concordant. Identical Twins, Discordant. Identical Twins, Concordant, plus additional ...Monozygotic (MZ) twins share nearly all of their genetic variants and many similar environments before and after birth. However, they can also show phenotypic discordance for a wide range of traits. Differences at the epigenetic level may account for such discordances. It is well established that epigenetic states can contribute to phenotypic variation, including disease. Epigenetic states are ...A six-fold increase in congenital heart defects (CHD) exists among monochorionic (MC) twins compared to singleton or dichorionic twin pregnancies. Though MC twins share an identical genotype, discordant phenotypes related to CHD and other malformations have been described, with reported rates of concordance for various congenital anomalies at less than 20%. Our objective was to characterize ...Thus, discordant moderate aortic stenosis (AS) became concordant moderate AS using the non-apical continuous wave Doppler data. Third, it is not clear how patients in atrial fibrillation were assessed. Atrial fibrillation was prevalent in these patients (213/790, 27%) and practice can vary from taking an average of 3 beats to an average of 5 ...Dec 01, 2009 · Microcalcifications alone were significantly more common in discordant than in concordant cancers. A limited number of studies have analyzed prospective independent double reading with respect to discordant and concordant cancers in mammography screening (10 –16). The studies showed discordant interpretation with subsequent cancers in 8.4% ... The hospital of admission was one of the strongest determinants of guideline concordance and accounted for one-fifth of the total variation in the blood glucose level at which insulin infusions were initiated. We did not identify associations between the hospital rate of guideline-concordant insulin use and hospital mortality.Aug 31, 2017 · Percent Discordance = (Number of discordant pairs)/Total number of pairs Percent Tied = (Number of tied pairs)/Total number of pairs Area under curve (c statistics) = Percent Concordant + 0.5 * Percent Tied. In general, higher percentages of concordant pairs and lower percentages of discordant and tied pairs indicate a more desirable model. ” Discordant latent classes can be identified in people with RA, and these findings are robust across three cohorts with varying disease duration and activity. These findings could be used to identify a sizeable subgroup of people with RA who might gain added benefit from pain management strategies. ... Concordant and discordant subgroups might ...The variation pattern lacks the simple harmonious relationships of the pure species. Variation is no longer con­ cordant, it.is DISCORDANT. It was by the discordance or concord­ ance of population variation patterns therefore that we had been able to rec­ ognize introgression in generaand in floras with which we were unfamiliar. In goodare concordant and discordant coastlines. The concordant coastline runs from west to east along the south coast. The discordant coastline runs from Studland Bay to Durlston Head as the geology changes from clay and sands, to chalk, to clay and sands again to limestone. Discordant and concordant coasts A wave-cut platform is formed when: The procedure for calculating concordant and discordant pairs compares the classifications for two variables (for example, X and Y) on the same two items. If the direction of classifications is the same, the pairs are concordant. For example, both X and Y rate item 1 higher than item 2.Concordant means to be harmonious and/or agreeable with. So keeping that in mind appendant would be any organization that has a requirement of being a freemason or close relations with a freemason to join. That would be Scottish Rite, Shrine (right now), York Rite, Eastern Star, Grotto, Amaranth, etc.For concordant modules, the control modules contained only non-concordant genes (including discordant genes, non-regulated genes or genes with significant differences only in one organism); for ...To explore the origins and potential clinical implications of dissimilarities between these two measures of LDL, we examined concordant and discordant subgroups separately, defining discordance as a difference of ≥12 percentile units to make half the population "concordant" (points between the dashed lines in Fig. 1B).Concordant and discordant coastlines. GCSE and A Level Geography Revision. Objectives To investigate the occurrence of discordant grading in patients with moderate AS (defined by an AVA between 1.0 cm² and 1.5 cm² but with an MG <20 mm Hg) and how these patients compare with those with concordant grading moderate AS (AVA between 1.0 cm² and 1.5 cm² and MG ≥20 mm Hg) in terms of clinical outcomes. Dec 28, 2019 · A drainage pattern is described as concordant if it correlates to the topology and geology of the area. In simple words, in a concordant drainage pattern, the path of the river is highly dependent on the slope of the river and topography. Concordant drainage patterns are the most commonly found drainage patterns and are classified into many ... Both liver fat concordant and discordant groups were equally discordant for BMI (mean BMI difference 5.9 kg/m 2 for the liver fat concordant and 4.9 kg/m 2 for the liver fat discordant, the distributions of BMI and liver fat discordances are shown in Additional file 2: Figure S1), as well as for subcutaneous and intra-abdominal fat (within-pair ...Methods: Motor impairment of sibling pairs from 67 ASD-affected families comprising 29 concordant pairings and 48 discordant pairings were assessed using the Bruininks Oseretsky Test of Motor Proficiency, 2nd Edition, a standardized measure of motor proficiency. However, when the measurements of FFR and NHPR are discordant (NHPRs+/FFR− or NHPRs−/FFR+) (as in ≈20% of cases), 9 the operator is ... deferred negative concordant and deferred discordant groups. Despite a prior study from the same registry 12 indicating nearly numerical equivalence among all of the diastolic NHPRs, the present study ...The variation pattern lacks the simple harmonious relationships of the pure species. Variation is no longer con­ cordant, it.is DISCORDANT. It was by the discordance or concord­ ance of population variation patterns therefore that we had been able to rec­ ognize introgression in generaand in floras with which we were unfamiliar. In goodJan 18, 2021 · Similar comparisons were made between CMV discordant (−/+, n = 5 pairs) and CMV concordant negative (−/−, n = 8 pairs) twins to assess the impacts of CMV. For the correlations within the age groups and CMV concordant negative pairs, the calculation was repeated 25 times with a random break up of each twin pair into the two groups to ... A six-fold increase in congenital heart defects (CHD) exists among monochorionic (MC) twins compared to singleton or dichorionic twin pregnancies. Though MC twins share an identical genotype, discordant phenotypes related to CHD and other malformations have been described, with reported rates of concordance for various congenital anomalies at less than 20%. Our objective was to characterize ...Thus, discordant moderate aortic stenosis (AS) became concordant moderate AS using the non-apical continuous wave Doppler data. Third, it is not clear how patients in atrial fibrillation were assessed. Atrial fibrillation was prevalent in these patients (213/790, 27%) and practice can vary from taking an average of 3 beats to an average of 5 ...were assigned randomly to nouns within a 3 (concordant, discordant, neutral) 3 2 (masculine vs feminine noun) 3 2 (transparent vs opaque noun) design, which permits a comparison of facilitation (RTs for concordant vs neutral pairs) and inhibition (RTs for discordant vs neutral pairs). Target nouns were never repeated within participants.Definitions. The opposition between consonance and dissonance can be made in different contexts: In acoustics or psychophysiology, the distinction may be objective. In modern times, it usually is based on the perception of harmonic partials of the sounds considered, to such an extent that the distinction really holds only in the case of harmonic sounds (i.e. sounds with harmonic partials).The rheumatology provider at the most recent clinical visit of a patient was a nurse practitioner or physician assistant for 230 patients (68%), attending physician for 90 (27%), and a fellow for 19 (6%), with no significant differences between the discordant and concordant groups (Table 1).The discordant group had a higher median global assessment of disease activity than the concordant group ...47.87 ± 13.99 years. Out of 282 lesions biopsied, 172 were concordant malignant and 105 were concordant benign. Two lesion out of 282 were borderline or high risk, one case was discordant benign and 2 cases discordant malignant. The appropriate management for all cases was recommended after radiology-pathology correlation. Concordant means to be harmonious and/or agreeable with. So keeping that in mind appendant would be any organization that has a requirement of being a freemason or close relations with a freemason to join. That would be Scottish Rite, Shrine (right now), York Rite, Eastern Star, Grotto, Amaranth, etc.Adjective. ( en adjective ) Agreeing; correspondent; harmonious; consonant; in keeping with; agreeable with; concordant with; concordant to. * Were every one employed in points concordant to their natures, professions, and arts, commonwealths would rise up of themselves.were assigned randomly to nouns within a 3 (concordant, discordant, neutral) 3 2 (masculine vs feminine noun) 3 2 (transparent vs opaque noun) design, which permits a comparison of facilitation (RTs for concordant vs neutral pairs) and inhibition (RTs for discordant vs neutral pairs). Target nouns were never repeated within participants.Uranium-bearing minerals that give lead-uranium and lead - lead ages that are essentially in agreement, i.e. concordant, generally are considered to have had a relatively simple geologic history and to have been unaltered since their deposition. The concordant ages obtained on such materials are, therefore, assumed to approach closely the actual age of the minerals. Many uranium-bearing ...A concordant coastline is where the same rock runs along the length of the coast. Concordant coastlines tend to have fewer bays and headlands. Find out more about concordant coastlines. ... What is a discordant coastline? Explain the formation of bays and headlands. Scroll to top.• There is significant variation in validation practices for IHC assays. ... (range 74-92%), with 2 of 5 studies >90% concordant. (Boers, 2011; Mayr, 2009; Moelans, 2010; O'Grady, 2010; van der Vegt, 2009) ... stratified by number of observed discordant samples . 2x2 contingency table of a 40 tissue validation set thatMay 09, 2008 · Background Physician treatment of cardiovascular risk factors may be affected by specific types of patient comorbidities. Objectives To examine the relationship between discordant comorbidities and LDL-cholesterol management in hypertensive patients not previously treated with lipid-lowering therapy; to determine whether the presence of cardiovascular (concordant) conditions mediates this ... Batholith: a large irregular discordant intrusion. Chonolith: an irregularly-shaped intrusion with a demonstrable base. Cupola: a dome-shaped projection from the top of a large subterranean intrusion. Dike: a relatively narrow tabular discordant body, often nearly vertical.May 09, 2015 · The PCs that followed these criteria (19 PCs, 37.2% of variation after PC3) represented patterns of inter-individual variation that were common between blood and brain tissues (Additional file 5: Figure S5). The first eight of the PCs identified by these criteria were positively correlated between blood and brain and captured 74.5% of the ... Dental caries remains the most common chronic disease in children, and the respective etiology is not fully understood. Though Streptococcus mutans is an important factor in the initiation and progression of caries, its presence is not always associated with the disease. The existence of caries discordant populations, in which S. mutans counts do not correlate with caries experience, poses a ...The Concordant Publishing Concern is a non-denominational, non-profit association founded for the purpose of disseminating the facts and truths of the ancient manuscripts of the Scriptures. Our research efforts are centered upon the many issues involved in discovering the meaning of the original Scripture terms themselves.Based on the correlation between the topology and the direction of flow, drainage patterns are classified into concordant drainage and discordant or insequent drainage. Concordant drainage patterns A drainage pattern is described as concordant if it correlates to the topology and geology of the area.Nov 25, 2021 · Objective To investigate whether alignment of strength of recommendations with quality of evidence differs in consensus based versus evidence based guidelines. Design Empirical analysis. Data source Guidelines developed by the American College of Cardiology and the American Heart Association (ACC/AHA) and the American Society of Clinical Oncology (ASCO) up to 27 March 2021. Study selection ... Methods: Motor impairment of sibling pairs from 67 ASD-affected families comprising 29 concordant pairings and 48 discordant pairings were assessed using the Bruininks Oseretsky Test of Motor Proficiency, 2nd Edition, a standardized measure of motor proficiency. Jun 25, 2018 · This actually indicates that there is discordant overlap (as confirmed in Fig. 5c), yet the interpretation of the colors is counterintuitive. The Stratified method (Fig. 5c), however, captures the true behavior of the studies. We can see that the discordant quadrants do have significant overlap, while the concordant quadrants do not. Nov 25, 2021 · Objective To investigate whether alignment of strength of recommendations with quality of evidence differs in consensus based versus evidence based guidelines. Design Empirical analysis. Data source Guidelines developed by the American College of Cardiology and the American Heart Association (ACC/AHA) and the American Society of Clinical Oncology (ASCO) up to 27 March 2021. Study selection ... Mar 29, 2021 · Reviewed on 3/29/2021. Concordant: 1. Showing concordance, complete agreement. A couple may be concordant for a sexually transmitted infection, with both partners having it. 2. In transplantation genetics, between closely related species. A concordant xenograft is a transplant between members of closely related species. discordant definition: 1. producing an unpleasant sound 2. used to describe something that is not in agreement with…. Learn more.19%) had discordant Doppler parame-ters—that is, a valve area of 1.0-1.5 cm2 but a mean gradient <20 mm Hg. Over a median follow-up period of 4.9 years, the discordant AS cohort were less likely to undergo aortic valve replacement (26.7% vs 44.1%) and had higher mortality (60% vs 43%) compared on July 12, 2022 by guest. Protected by copyright.An environmentally mediated increase in temporal activity and a genetically mediated increase in parietal activity have also been observed in a previous study by our group that used the discordant/concordant twin design to study OC symptom-related brain alterations during a cognitive planning paradigm (den Braber et al., Reference den Braber ...( A) Algorithm used to identify concordant and discordant gene modules. The log fold changes and p-values between groups were calculated with R-package limma. The orthologous genes or genes corresponding to each other (if compared data sets derive from two groups of the same species) were mapped to each other.Discordant latent classes can be identified in people with RA, and these findings are robust across three cohorts with varying disease duration and activity. These findings could be used to identify a sizeable subgroup of people with RA who might gain added benefit from pain management strategies. ... Concordant and discordant subgroups might ...If the distance between R1 and R2 is outside 500bp (+/- 1SD) or they relative orientation is not Forward/Reverse thy will be called as discordant pairs. If R1 (or R2) alone are aligned, this will...Jun 03, 2020 · While concordant phenotypes of non-VI/non-OB and VI/OB had a clear separation of disease burden in terms of PROs and emphysema, the discordant phenotypes of VI/non-OB and non-VI/OB resembled more their VI status than their OB status. Our data suggests that up to 19% of COPD subjects may be misclassified using SP. types of cry in pediatric dentistry pptlawrenceville country clubkillmare lemon wattpadanna sorokin